PART 1 FOUNDATIONS OF CLINICAL DERMATOLOGY
1 Fundamentals of Clinical Dermatology: Morphology and Special Clinical Considerations Page1
2 Pathology of Skin Lesions Page18
3 Epidemiology and Public Health in Dermatology Page40 |
PART 17 DISORDERS DUE TO THE ENVIRONMENT
92 Polymorphic Light Eruption Page1611
93 Actinic Prurigo Page1628
94 Hydroa Vacciniforme Page1634
95 Actinic Dermatitis Page1639
96 Solar UrticariaPage1650
97 Phototoxicity and Photoallergy Page1657
98 Cold Injuries Page1666
99 Burns Page1679 |
PART 2 STRUCTURE AND FUNCTION OF SKIN
4 Developmental Biology of the Skin Page49
5 Growth and Differentiation of the Epidermis Page62
6 Skin Glands: Sebaceous, Eccrine, and Apocrine Glands Page70
7 Biology of Hair Follicles Page89
8 Nail Page Page106
9 Cutaneous Vasculature Page 116
10 The Immunological Structure of the Skin Page130
11 Cellular Components of the Cutaneous Immune System Page143
12 Soluble Mediators of the Cutaneous Immune System Page159
13 Basic Principles of Immunologic Diseases in Skin (Pathophysiology of Immunologic/Infammatory Skin Diseases) Page192
14 Skin Barrier Page206
15 Epidermal and Dermal Adhesion Page232
16 Microbiome of the Skin Page253
17 Cutaneous Photobiology Page265
18 Genetics in Relation to the Skin Page289
19 Carcinogenesis and SkinPage310
20 Pigmentation and Melanocyte Biology Page328
21 Neurobiology of the Skin Page351 |
PART 18 PSYCHOSOCIAL SKIN DISEASE
100 Delusional, Obsessive-Compulsive, and Factitious Skin Diseases Page1693
101 Drug Abuse Page Page1705
102 Physical Abuse Page1717 |
PART 3 DERMATITIS
22 Atopic Dermatitis Page363
23 Nummular Eczema, Lichen Simplex Chronicus, and Prurigo Nodularis Page385
24 Allergic Contact Dermatitis Page395
25 Irritant Dermatitis Page414
26 Seborrheic Dermatitis Page428
27 Occupational Skin Diseases Page438 |
PART 19 SKIN CHANGES ACROSS THE SPAN OF LIFE
103 Neonatal Dermatology Page1727
104 Pediatric and Adolescent Dermatology Page1750
105 Skin Changes and Diseases in Pregnancy Page1765
106 Skin Aging Page1779
107 Caring for LGBT Persons in Dermatology Page1792 |
PART 4 PSORIASIFORM DISORDERS
28 Psoriasis Page457
29 Pityriasis Rubra Pilaris Page498
30 Parapsoriasis and Pityriasis Lichenoides Page505
31 Pityriasis Rosea Page518 |
PART 20 NEOPLASIA
108 Benign Epithelial Tumors, Hamartomas, and Hyperplasias Page1799
109 Appendage Tumors of the Skin Page1820
110 Epithelial Precancerous Lesions Page1857
111 Basal Cell Carcinoma and Basal Cell Nevus Syndrome Page1884
112 Squamous Cell Carcinoma and Keratoacanthoma Page1901
113 Merkel Cell Carcinoma Page1920
114 Paget?s Disease Page1934
115 Melanocytic Nevi Page1944
116 Melanoma Page1982
117 Histiocytosis Page2018
118 Vascular Tumors Page2042
119 Cutaneous Lymphoma Page2072
120 Cutaneous Pseudolymphoma Page2108
121 Neoplasias and Hyperplasias of Muscular and Neural Origin Page2130
122 Lipogenic Neoplasms Page2172 |
PART 5 LICHENOID AND GRANULOMATOUS DISORDERS
32 Lichen Planus Page527
33 Lichen Nitidus and Lichen Striatus Page554
34 Granuloma Annulare Page564
35 Sarcoidosis Page572 |
PART 21 METABOLIC, GENETIC, AND SYSTEMIC DISEASES
123 Cutaneous Changes in Nutritional Disease Page2199
124 The Porphyrias Page2234
125 Amyloidosis Page2258
126 Xanthomas and Lipoprotein Disorders Page2273
127 Fabry Disease Page2292
128 Calcium and Other Mineral Deposition Disorders Page2307
129 Graft-Versus-Host Disease Page2320
130 Hereditary Disorders of Genome Instability and DNA Repair Page2342
131 Ectodermal Dysplasias Page2372
132 Genetic Immunode?ciency Diseases Page Page2394
133 Skin Manifestations of Internal Organ Disorders Page2425
134 Cutaneous Paraneoplastic Syndromes Page2441
135 The Neurofibromatoses Page2465
136 Tuberous Sclerosis Complex Page2480
137 Diabetes and Other Endocrine Diseases Page2493 |
PART 6 NEUTROPHILIC, EOSINOPHILIC, AND MAST CELL DISORDERS
36 Sweet Syndrome Page587
37 Pyoderma Gangrenosum Page605
38 Subcorneal Pustular Dermatosis (Sneddon-Wilkinson Disease) Page617
39 Autoinfammatory Disorders Page621
40 Eosinophilic Diseases Page Page649
41 Urticaria and Angioedema Page684
42 Mastocytosis Page710 |
PART 22 VASCULAR DISEASES
138 Cutaneous Necrotizing Venulitis Page2527
139 Systemic Necrotizing Arteritis Page2539
140 Erythema Elevatum Diutinum Page2562
141 Adamantiades?Behcet Disease Page2567
142 Kawasaki Disease Page2580
143 Pigmented Purpuric Dermatoses Page2590
144 Cryoglobulinemia and Cryofibrinogenemia PagePage2599
145 Raynaud Phenomenon Page2613
146 Malignant Atrophic Papulosis (Degos Disease) PagePage2630
147 Vascular Malformations Page2636
148 Cutaneous Changes in Arterial, Venous, and Lymphatic Dysfunction Page2669
149 Wound Healing Page2700 |
PART 7 REACTIVE ERYTHEMAS
43 Erythema Multiforme Page Page723
44 Epidermal Necrolysis (Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis) Page733
45 Cutaneous Reactions to Drugs Page749
46 Erythema Annulare Centrifugum and Other Figurate Erythemas Page765 |
PART 23 BACTERIAL DISEASES
150 Superficial Cutaneous Infections and Pyodermas Page2719
151 Cellulitis and Erysipelas Page2746
152 Gram-Positive Infections Associated with Toxin Production Page2757
153 Necrotizing Fasciitis, Necrotizing Cellulitis, and Myonecrosis Page2770
154 Gram-Negative Coccal and Bacillary Infections Page Page2782
155 The Skin in Infective Endocarditis, Sepsis, Septic Shock, and Disseminated Intravascular Coagulation Page2815
156 Miscellaneous Bacterial Infections with Cutaneous Manifestations Page2827
157 Tuberculosis and Infections with Atypical Mycobacteria Page2858
158 Actinomycosis, Nocardiosis, and Actinomycetoma Page2876
159 Leprosy Page2892 |
PART 8 DISORDERS OF CORNIFICATION
47 The Ichthyoses Page775
48 Inherited Palmoplantar Keratodermas Page Page816
49 Keratosis Pilaris and Other Follicular Keratotic Disorders Page867
50 Acantholytic Disorders of the Skin Page877
51 Porokeratosis Page901 |
PART 24 FUNGAL DISEASES
160 Superficial Fungal Infection Page2925
161 Yeast Infections Page2952
162 Deep Fungal Infections Page2965 |
PART 9 VESICULOBULLOUS DISORDERS
52 Pemphigus Page909
53 Paraneoplastic Pemphigus Page934
54 Bullous Pemphigoid Page Page944
55 Mucous Membrane Pemphigoid Page960
56 Epidermolysis Bullosa Acquisita Page971
57 Intercellular Immunoglobulin (Ig) A Dermatosis (IgA Pemphigus) Page981
58 Linear Immunoglobulin A Dermatosis and Chronic Bullous Disease of Childhood Page Page992
59 Dermatitis Herpetiformis Page1002
60 Inherited Epidermolysis Bullosa Page1011 |
PART 25 VIRAL DISEASES
163 Exanthematous Viral Diseases Page2989
164 Herpes Simplex Page3021
165 Varicella and Herpes ZosterPage3035
166 Poxvirus Infections Page Page3065
167 Human Papillomavirus Infections Page3095
168 Cutaneous Manifestations of HIV and Human T-Lymphotropic Virus Page3107
169 Mosquito-Borne Viral Diseases Page3135 |
PART 10 AUTOIMMUNE CONNECTIVE TISSUE AND RHEUMATOLOGIC DISORDERS
61 Lupus Erythematosus Page1037
62 Dermatomyositis Page1061
63 Systemic Sclerosis Page1086
64 Morphea and Lichen Sclerosus Page1106
65 Psoriatic Arthritis and Reactive Arthritis Page1127
66 Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, Adult-Onset Still Disease, and Rheumatic Fever Page1146
67 Scleredema and Scleromyxedema Page1163
68 Sjogren Syndrome Page1170
69 Relapsing Polychondritis Page1186 |
PART 26 SEXUALLY TRANSMITTED DISEASES
170 Syphilis Page3145
171 Endemic (Nonvenereal) Treponematoses Page3173
172 Chancroid Page3186
173 Lymphogranuloma Venereum Page3193
174 Granuloma Inguinale Page3202
175 Gonorrhea, Mycoplasma, and Vaginosis Page3207 |
PART 11 DERMAL CONNECTIVE TISSUE DISORDERS
70 Anetoderma and Other Atrophic Disorders of the Skin Page1193
71 Acquired Perforating Disorders PagePage1203
72 Genetic Disorders Affecting Dermal Connective Tissue Page1212 |
PART 27 INFESTATIONS, BITES, AND STINGS
176 Leishmaniasis and Other Protozoan Infections Page3223
177 Helminthic Infections Page3251
178 Scabies, Other Mites, and Pediculosis Page Page3274
179 Lyme BorreliosisPage3287
180 The Rickettsioses, Ehrlichioses, and Anaplasmoses Page3306
181 Arthropod Bites and Stings Page3324
182 Bites and Stings of Terrestrial and Aquatic Life Page3338 |
PART 12 SUBCUTANEOUS TISSUE DISORDERS
73 Panniculitis PagePage1251
74 Lipodystrophy Page1295 |
PART 28 TOPICAL AND SYSTEMIC TREATMENTS
183 Principles of Topical Therapy Page3363
184 Glucocorticoids Page3382
185 Retinoids Page3395
186 Systemic and Topical Antibiotics Page3407
187 Dapsone Page3423
188 Antifungals Page3436
189 Antihistamines Page3451
190 Cytotoxic and Antimetabolic Agents PagePage3463
191 Antiviral Drugs Page3493
192 Immunosuppressive and Immunomodulatory Drugs Page3517
193 Immunobiologics: Targeted Therapy Against Cytokines, Cytokine Receptors, and Growth Factors in Dermatology Page3531
194 Molecular Targeted Therapies Page3558
195 Antiangiogenic Agents Page3590
196 Other Topical Medications Page3610
197 Photoprotection Page3623 |
PART 13 MELANOCYTIC DISORDERS
75 Albinism and Other Genetic Disorders of Pigmentation Page1309
76 Vitiligo Page1330
77 Hypermelanoses Page1351 |
PART 29 PHYSICAL TREATMENTS
198 Phototherapy Page3635
199 Photochemotherapy and Photodynamic Therapy Page3664
200 Radiotherapy Page3687 |
PART 14 ACNEIFORM DISORDERS
78 Acne Vulgaris Page1391
79 Rosacea Page1419
80 Acne Variants and Acneiform EruptionsPage1448 |
PART 30 DERMATOLOGIC SURGERY
201 Cutaneous Surgical Anatomy Page3697
202 Perioperative Considerations in Dermatologic Surgery Page3706
203 Excisional Surgery and Repair, Flaps, and Grafts Page3726
204 Mohs Micrographic Surgery Page3761
205 Nail Surgery Page3774
206 Cryosurgery and ElectrosurgeryPage3791 |
PART 15 DISORDERS OF ECCRINE AND APOCRINE SWEAT GLANDS
81 Hyperhidrosis and Anhidrosis Page1459
82 Bromhidrosis and Chromhidrosis Page1469
83 Fox-Fordyce Disease Page Page1475
84 Hidradenitis Suppurativa Page1480 |
PART 31 COSMETIC DERMATOLOGY
207 Cosmeceuticals and Skin Care in Dermatology Page3803
208 Fundamentals of Laser and Light-Based Treatments Page3820
209 Laser Skin Resurfacing: Cosmetic and Medical Applications Page3834
210 Nonablative Laser and Light-Based Therapy: Cosmetic and Medical Indications Page3846
211 Noninvasive Body Contouring Page3857
212 Treatment of Varicose Veins and Telangiectatic Lower-Extremity Vessels Page3871
213 Chemical Peels and Dermabrasion Page3895
214 Liposuction Using Tumescent Local Anesthesia Page3906
215 Soft-Tissue Augmentation Page3911
216 Botulinum Toxin Page3921
217 Hair Transplantation PagePage3931 |
PART 16 DISORDERS OF THE HAIR AND NAILS
85 Androgenetic Alopecia Page1495
86 Telogen Effluvium Page1507
87 Alopecia Areata Page1517
88 Cicatricial Alopecias Page Page1524
89 Hair Shaft Disorders Page Page1537
90 Hirsutism and Hypertrichosis Page1555
91 Nail Disorders Page1568 |
INDEX |
