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CEB Data Warehouse

Introduction

Data warehouses for non-communicable diseases (NCDs) from Ramathibodi hospital information system focusing on metabolic syndrome atherosclerosis, cancer and surgery including type 2 diabetes (T2D), hypertension (HT), chronic kidney disease (CKD), cardiovascular disease (CVDs), atrial fibrillation (AF), stroke, prostate cancer and surgery were constructed and updated from 2010 to 2020.

Treatment managements of each disease can be assessed based on these real-world data which much reflect current clinical practice in Thailand. Disease prognosis can be assessed. And incorporate with treatment effectiveness, this will lead to delay development of complications and thus prolong patients’ survival, improve quality of life, and reduce economic loss from disease burden. These data warehouses will be updated regularly and open to general researchers in and outside the Faculty of Medicine Ramathibodi Hospital to utilize these data for conducting research after ethics committee approval.

The data flows and structures for each cohort are as follow:

T2D ( N = 71,953 )

Ongoing research topics

  • Multi-state model
  • Treatment effectiveness of second-line drugs in prevention of heart failure
  • Prognostic factors of heart failure in T2D patients
  • Effect of second-line drugs on CVD, CKD, All-cause mortality
  • Effect of second-line drugs on diabetic ratinopathy 
  • Effect of second-line drugs on fatty liver (NAFLD/NASH)
  • Effect of GLP1 on BMI
  • Cost-Utility Analysis of Laparoscopic Bariatric Surgery for Obesity with type II Diabetes Mellitus
  • Effects of second-line drugs in lowering PAD occurrence 
  • Hypoglycemic events  and economic evaluation in treatment managements of T2D patients
  • Short and Long term outcomes between patients who are treated in DM clinic vs non-DM clinic

CKD ( N = 51,530 )

HT

Ongoing research topic

  • Disease Progresssion of Hypertension Using Machine Learning 

Stroke ( N of Ischemic stroke = 8,842 & N of Hemorrhagic stroke = 3,014 )

Ongoing research topic

  • Intelligence System and Casual Analysis in Stroke

AF

Ongoing research topic

  • Real-world effectiveness and safety of direct oral anticoagulants and warfarin in patients with atrial fibrillatio

Prostate Cancer

Ongoing research topics

  • Using deep learning algorithm for Gleason grading of prostate cancer from biopsy specimens
  • The association of prostate-specific antigen (PSA) threshold with prostate cancer changing stage and progression: Real world data

Surgery

Ongoing research topic

  • Incisional Hernia and Fascial Dehiscence prediction model
 
Department of Clinical Epidemiology and Biostatistics